Abstract
Peptide nucleic acid fluorescence in situ hybridization (PNA FISH) was instituted at Boston Medical Center for the rapid identification of coagulase-negative staphylococci (CoNS). Without active notification or antimicrobial stewardship intervention, a pre- and postimpact analysis showed no benefit of this assay with respect to the length of hospital stay or vancomycin use.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Academic Medical Centers
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Anti-Bacterial Agents / therapeutic use*
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Bacteriological Techniques / methods*
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Boston
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Coagulase / metabolism
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Drug Utilization / statistics & numerical data
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Female
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Fluorescence
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Humans
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In Situ Hybridization / methods*
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Length of Stay
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Male
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Peptide Nucleic Acids*
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Staphylococcal Infections / diagnosis*
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Staphylococcal Infections / microbiology
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Staphylococcus / enzymology
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Staphylococcus / genetics
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Staphylococcus / isolation & purification*
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Treatment Outcome
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Vancomycin / therapeutic use
Substances
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Anti-Bacterial Agents
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Coagulase
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Peptide Nucleic Acids
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Vancomycin