A deficiency chromosome in Drosophila alters neuritic projections in an identified motoneuron

Brain Res. 1990 Dec 3;535(1):147-50. doi: 10.1016/0006-8993(90)91833-3.


The tergotrochanteral muscles (TTM) in the second thoracic segment of the fruitfly, Drosophila melanogaster, power the jump-escape response. The cell bodies of the motoneurons innervating these muscles, located in the thoracico-abdominal ganglion, have prominent posterior and medial neurites. While in wildtype flies of the Canton-S (C-S) and Oregon-R (O-R) strains, the medial neurite of a TTM motoneuron rarely crossed the midline (C-S: 0/17; O-R: 2/8), in heterozygous flies with a deficiency at the base of the X-chromosome, Df(1)16-3-22, the medial neurite frequently crossed the midline (Df(1)16-3-22/C-S: 7/12; Df(1)16-3-22/O-R: 18/22).

MeSH terms

  • Animals
  • Axons / ultrastructure*
  • Chromosome Mapping
  • Drosophila melanogaster / genetics*
  • Drosophila melanogaster / ultrastructure
  • Female
  • Gene Frequency / genetics
  • Genotype
  • Male
  • Motor Neurons / ultrastructure*
  • X Chromosome*