Efficacy of ultrasound-guided steroid injections for pain management of midfoot joint degenerative disease

Skeletal Radiol. 2011 Aug;40(8):1001-6. doi: 10.1007/s00256-010-1094-y. Epub 2011 Jan 28.


Objective: To examine the efficacy of ultrasound (US)-guided injections for midfoot joint degenerative changes.

Materials and methods: The US images and radiographs of 63 patients with midfoot joint degenerative changes were retrospectively reviewed. In those patients who had US-guided intra-articular steroid injection, the response to the injection was recorded by reviewing the 2-week pain diaries and clinical notes. Partial or complete pain relief was defined as a positive response and the same or increased level of pain as a negative response to the injection.

Results: Fifty-nine (59/63, 93.6%) patients with midfoot joint degenerative changes received US-guided injection. The majority of patients had a positive response up to 3 months post-injection (78.4% still experiencing pain relief at 2 weeks, 57.5% at 3 months and fewer than 15% of patients further than 3 months post-injection). The number of positive therapeutic responses did not differ significantly between patients with diagnostic and non-diagnostic response (p = 0.2636).

Conclusions: US-guided intra-articular injections for midfoot degenerative changes can have a good therapeutic result in the majority of patients up to 3 months post-injection. Therapeutic response cannot be predicted by a positive diagnostic response.

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / therapeutic use*
  • Aged
  • Aged, 80 and over
  • Female
  • Foot Diseases / diagnostic imaging
  • Foot Diseases / drug therapy*
  • Humans
  • Injections, Intra-Articular
  • Male
  • Middle Aged
  • Osteoarthritis / diagnostic imaging
  • Osteoarthritis / drug therapy*
  • Pain / drug therapy*
  • Pain Measurement
  • Radiography
  • Retrospective Studies
  • Treatment Outcome
  • Ultrasonography, Interventional*


  • Adrenal Cortex Hormones