Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase

ChemMedChem. 2011 Feb 7;6(2):266-72. doi: 10.1002/cmdc.201000343. Epub 2010 Nov 10.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Hydro-Lyases / antagonists & inhibitors*
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Protein Conformation
  • Thiophenes / chemistry
  • Thiophenes / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Enzyme Inhibitors
  • Thiophenes
  • benzothiophene
  • Hydro-Lyases
  • 3-dehydroquinate dehydratase