Pregnancy in cystic fibrosis

Clin Chest Med. 2011 Mar;32(1):111-120. doi: 10.1016/j.ccm.2010.10.005.


The challenges posed by cystic fibrosis (CF), including poor nutrition and progressive lung function decline, may pose problems for pregnancy for both mother and child. A multidisciplinary team of providers is optimal to help address the variety of issues that might arise in such a pregnancy. Careful attention to maternal weight gain, pulmonary function and exacerbations, and screening for gestational diabetes is necessary. Pregnancies among women with CF are associated with more frequent use of intravenous antibiotics and hospitalization than is seen in nonpregnant CF women. This article reviews maternal and fetal outcomes for CF in pregnancy.

Publication types

  • Review

MeSH terms

  • Cystic Fibrosis* / epidemiology
  • Cystic Fibrosis* / genetics
  • Cystic Fibrosis* / physiopathology
  • Cystic Fibrosis* / therapy
  • Delivery, Obstetric
  • Diabetes, Gestational / etiology
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Fertility / physiology
  • Forced Expiratory Volume
  • Genetic Testing
  • Humans
  • Lung / physiopathology
  • Lung Transplantation
  • Malnutrition / etiology
  • Maternal Mortality
  • Pregnancy
  • Pregnancy Complications* / epidemiology
  • Pregnancy Complications* / genetics
  • Pregnancy Complications* / physiopathology
  • Pregnancy Complications* / therapy
  • Pregnancy Outcome
  • Teratogens


  • Teratogens