Comparative expression of the mRNA for three intestinal hydrolases during postnatal development in the rat

Cell Mol Biol. 1990;36(6):729-36.


The distribution of the mRNA for intestinal aminopeptidase-N, lactase-phlorizin hydrolase and sucrase-isomaltase was compared during rat postnatal development as well as along the longitudinal axis of the intestinal tract including small-intestine and colon. We found out that each mRNA exhibited a specific pattern of accumulation, suggesting proper regulation steps for the expression of the corresponding digestive enzymes.

MeSH terms

  • Aminopeptidases / genetics*
  • Animals
  • Colon / chemistry
  • DNA Probes
  • Gene Expression Regulation, Enzymologic
  • Ileum / chemistry
  • Jejunum / chemistry
  • RNA, Messenger / analysis*
  • Rats
  • Rats, Inbred Strains / growth & development
  • beta-Galactosidase / genetics*


  • DNA Probes
  • RNA, Messenger
  • beta-Galactosidase
  • Aminopeptidases