In this study, marginal adaptations of different copings fabricated with CAD/CAM or MAD/CAM were analysed. Celay and Zirkonzahn groups were fabricated by MAD/CAM, LAVA and DC-Zircon groups were fabricated by CAD/CAM. Casting metal copings were used as the control group. An implant abutment that was embedded in octagonal acrylic block was used to prepare the copings. Sixteen previously established points were marked and the measurements were performed with the stereomicroscope (at × 150). The marginal fit of the samples were evaluated by calculating the mean measurements of each 16 points. The statistical analysis was performed by Tukey multiple comparisons test at 95% confidence interval. The groups can be summarized as follows in terms of marginal gap, from the lowest to highest: LAVA (24.6 ± 14.0 µm)<Celay (64.9 ± 25.2 µm)<DC-Zircon (110.1 ± 36.5 µm)<Zirkonzahn (112.11 ± 22.6 µm)<InvalidTagl (120.1 ± 33.1 µm). Usage of CAD/CAM or MAD/CAM systems may not be the most important factor for marginal adaptation.