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. 2010 Feb;6(1):54-61.
doi: 10.2174/157340310790231635.

Sleep Duration as a Risk Factor for Cardiovascular Disease- A Review of the Recent Literature

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Free PMC article

Sleep Duration as a Risk Factor for Cardiovascular Disease- A Review of the Recent Literature

Michiaki Nagai et al. Curr Cardiol Rev. .
Free PMC article

Abstract

Sleep loss is a common condition in developed countries, with evidence showing that people in Western countries are sleeping on average only 6.8 hour (hr) per night, 1.5 hr less than a century ago. Although the effects of sleep deprivation on our organs have been obscure, recent epidemiological studies have revealed relationships between sleep deprivation and hypertension (HT), coronary heart disease (CHD), and diabetes mellitus (DM). This review article summarizes the literature on these relationships. Because sleep deprivation increases sympathetic nervous system activity, this increased activity serves as a common pathophysiology for HT and DM. Adequate sleep duration may be important for preventing cardiovascular diseases in modern society.

Keywords: Sleep duration; coronary heart disease; diabetes mellitus.; hypertension.

Figures

Fig. (1)
Fig. (1)
Means of ambulatory blood pressure on a normal workday and a sleep-insufficient day. BP indicates blood pressure; SBP1, systolic BP on sleep-insufficient day; SBP2, systolic BP on normal workday; DBP1, diastolic BP on sleep-insufficient day; DBP2, diastolic BP on normal workday. (From Tochikubo et al. [16]. Hypertension 1996; 27: 1318-1324).
Fig. (2)
Fig. (2)
Chart for the relationships between sleep deprivation and hypertension, diabetes mellitus, and coronary heart disease.
Fig. (3)
Fig. (3)
Means of ambulatory blood pressure after repeated melatonin and repeated placebo sadministration. The light-gray background indicates the average period in bed. (From Scheer et al. (66). Hypertension 2004; 43: 192-197).

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