Attribution of Congenital Cytomegalovirus Infection to Primary Versus Non-Primary Maternal Infection

Clin Infect Dis. 2011 Jan 15;52(2):e11-3. doi: 10.1093/cid/ciq085.

Abstract

Congenital cytomegalovirus (CMV) infection is a leading cause of developmental disabilities. In the United States during the period 1988-1994, approximately one-quarter of congenital CMV infections were attributable to primary maternal infection (n = 8772), and three-quarters were attributable to non-primary maternal infection (n = 29,918). Effective prevention strategies need to be developed for both primary and non-primary maternal infections.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / congenital*
  • Cytomegalovirus Infections / epidemiology*
  • Cytomegalovirus Infections / prevention & control
  • Female
  • Humans
  • Infant, Newborn
  • Middle Aged
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / prevention & control
  • Pregnancy Complications, Infectious / virology*
  • Prevalence
  • United States / epidemiology
  • Young Adult