Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes

Biochimie. 1990 Dec;72(12):889-91. doi: 10.1016/0300-9084(90)90008-5.


The protein patterns of a bglY mutant and the isogenic wild-type strains were compared on 2-dimensional gel electrophoresis. The synthesis of at least 36 peptides was affected. This suggests a global but specific role on gene expression for the DNA-binding protein H1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Bacterial Proteins / isolation & purification
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / isolation & purification
  • Electrophoresis, Gel, Two-Dimensional
  • Escherichia coli / genetics*
  • Gene Expression Regulation, Bacterial
  • Genes
  • Genes, Bacterial
  • Mutation


  • Bacterial Proteins
  • DNA-Binding Proteins
  • H-NS protein, bacteria