High-speed Droplet Generation on Demand Driven by Pulse Laser-Induced Cavitation

Lab Chip. 2011 Mar 21;11(6):1010-2. doi: 10.1039/c0lc00555j. Epub 2011 Feb 2.


We report on a pulse laser-driven droplet generation (PLDG) mechanism that enables on-demand droplet generation at rates up to 10,000 droplets per second in a single-layer PDMS-based microfluidic device. Injected droplet volumes can be continuously tuned between 1 pL and 150 pL with less than 1% volume variation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Dimethylpolysiloxanes / chemistry
  • Lasers*
  • Microfluidic Analytical Techniques / instrumentation*
  • Microfluidic Analytical Techniques / methods
  • Nylons / chemistry


  • Dimethylpolysiloxanes
  • Nylons
  • poly(dimethylsiloxane)-polyamide copolymer