Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi

Nat Prod Rep. 2011 Apr;28(4):809-23. doi: 10.1039/c0np00069h. Epub 2011 Feb 3.

Abstract

Here, we review studies that have investigated the activity of plant-derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas’ disease. In the last decade, more than 300 species belonging to almost 100 families have been evaluated for activity, and here we describe the compounds isolated; 85 references are cited.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Products* / chemistry
  • Biological Products* / isolation & purification
  • Biological Products* / pharmacology
  • Chagas Disease* / drug therapy
  • Chagas Disease* / etiology
  • Chagas Disease* / immunology
  • Humans
  • Plants, Medicinal / chemistry*
  • Trypanosoma cruzi / drug effects*
  • Trypanosoma cruzi / immunology

Substances

  • Biological Products