Assessment of body composition in peritoneal dialysis patients using bioelectrical impedance and dual-energy x-ray absorptiometry

Am J Nephrol. 2011;33(2):150-6. doi: 10.1159/000324111. Epub 2011 Feb 3.


Introduction: Protein energy wasting is closely related to increased morbidity and mortality in peritoneal dialysis (PD) patients. Simple reliable and easily available methods of determining nutritional status and recognition of short-term changes in body composition are therefore important for clinical practice.

Methods: We compared whole-body and segmental composition using multifrequency bioelectrical impedance analysis (MF-BIA) and dual-energy X-ray absorptiometry (DEXA) in 104 stable PD patients.

Results: Assessment of whole-body composition showed that lean body mass (LBM) was highly correlated with good method agreement using DEXA as the reference test (r = 0.95, p < 0.0001; bias -0.88 kg, 95% CI -1.53 to 0.23 kg). Similarly, high correlation and good method agreement were found for fat mass (r = 0.93, p < 0.0001; bias 0.69 kg, 95% CI 0.03-1.36 kg). Segmental analysis of LBM revealed strong correlations between LBM for trunk, left and right arms and legs (r = 0.90, 0.84, 0.86, 0.89 and 0.90, respectively, p < 0.0001). Bone mineral content derived by MF-BIA overestimated that measured by DEXA (bias 0.740 kg, 95% CI 0.66-0.82 kg).

Conclusion: MF-BIA may potentially be a useful tool for determining nutritional status in PD patients and serial estimations may help recognize short-term changes in body composition.

MeSH terms

  • Absorptiometry, Photon / methods*
  • Adult
  • Aged
  • Aged, 80 and over
  • Body Composition*
  • Body Mass Index
  • Bone Density
  • Electric Impedance*
  • Female
  • Humans
  • Kidney Failure, Chronic / diagnostic imaging
  • Kidney Failure, Chronic / therapy
  • Male
  • Middle Aged
  • Nutritional Status
  • Peritoneal Dialysis / methods*