Cross-coupling of mesylated phenol derivatives with potassium ammonio- and amidomethyltrifluoroborates

Org Lett. 2011 Mar 4;13(5):1242-5. doi: 10.1021/ol200128y. Epub 2011 Feb 4.

Abstract

A large array of aryl and heteroaryl mesylates have been successfully employed as electrophiles in a Csp(2)-Csp(3) Suzuki-Miyaura cross-coupling with potassium ammonio- and amidomethyltrifluoroborates to afford the corresponding products in high yields.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Borates / chemistry*
  • Catalysis
  • Combinatorial Chemistry Techniques
  • Mesylates / chemistry*
  • Molecular Structure
  • Phenols / chemistry*
  • Potassium / chemistry*
  • Salts

Substances

  • Borates
  • Mesylates
  • Phenols
  • Salts
  • Potassium