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. 2011 Sep;20(7):1131-40.
doi: 10.1007/s11136-011-9849-z. Epub 2011 Feb 5.

Health-related quality of life in adults reporting arthritis: analysis from the National Health Measurement Study

Dinesh Khanna  1 , Paul Maranian, Mari Palta, Robert M Kaplan, Ron D Hays, Dasha Cherepanov, Dennis G Fryback
Affiliations

Health-related quality of life in adults reporting arthritis: analysis from the National Health Measurement Study

Dinesh Khanna et al. Qual Life Res. 2011 Sep.

Abstract

Background: Arthritis is the leading cause of disability in the United States. We assess the generic health-related quality-of-life (HRQOL) among a nationally representative sample of U.S. adults with and without self-reported arthritis.

Methods: The NHMS, a cross-sectional survey of 3,844 adults (35-89 years) administered EuroQol-5D (EQ-5D), Health Utilities Index Mark 2 (HUI2) and 3 (HUI3), SF-36v2™, Quality of Well-being Scale self-administered form (QWB-SA), and the Health and Activities Limitations index (HALex) to each respondent via a telephone interview. Weighted multiple linear regression was used to generate age-gender-arthritis-stratified unadjusted HRQOL means and means adjusted for sociodemographic, socioeconomic covariates and comorbidities by arthritis-age category.

Results: The estimated population prevalence of self-reported arthritis was 31%. People with arthritis were more likely to be woman, older, of lower socioeconomic status, and had more self-reported comorbidities than were those not reporting arthritis. Adults with arthritis had lower HRQOL on six different indexes compared with adults without arthritis, with overall differences ranging from 0.03 (QWB-SA, age-group 65-74) to 0.17 (HUI3, age-group 35-44; all P-value < .05).

Conclusion: Arthritis in adults is associated with poorer HRQOL. We provide age-related reference values for six generic HRQOL measures in people with arthritis.

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Figures

Fig. 1
Fig. 1
Means (SE) estimating non-institutionalized US population health-related quality-of-life (HRQOL) by age are shown for self-reported arthritis and no arthritis using 6 standardized indexes. The mean estimates are adjusted for gender, race, level of education, annual household income body mass index, and the presence or absence of the following self-reported health care professional-diagnosed comorbidities: coronary heart disease, diabetes, stroke, COPD, and sleeping disorder
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