Strategy for intention to treat analysis in randomised trials with missing outcome data

BMJ. 2011 Feb 7:342:d40. doi: 10.1136/bmj.d40.


Loss to follow-up is often hard to avoid in randomised trials. This article suggests a framework for intention to treat analysis that depends on making plausible assumptions about the missing data and including all participants in sensitivity analyses

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Intention to Treat Analysis / methods*
  • Randomized Controlled Trials as Topic / methods*
  • Sensitivity and Specificity
  • Treatment Outcome