Multidisciplinary management of early and locally advanced esophageal cancer

J Clin Gastroenterol. 2011 May-Jun;45(5):391-9. doi: 10.1097/MCG.0b013e3182049949.


Clinical management of esophageal cancer is a multidisciplinary challenge. Diagnosis is associated with a high mortality and approximately 40% of patients have locally advanced disease at clinical presentation. Surgery remains one of the fundamental parts of treatment, but multimodal approaches including chemotherapy and radiation are associated with improved outcomes. This comprehensive review addresses the multidisciplinary management of early and locally advanced esophageal cancer.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Esophageal Neoplasms* / drug therapy
  • Esophageal Neoplasms* / pathology
  • Esophageal Neoplasms* / radiotherapy
  • Esophageal Neoplasms* / surgery
  • Humans
  • Radiotherapy
  • Treatment Outcome


  • Antineoplastic Agents