Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodies

Lupus. 2011 Feb;20(2):206-18. doi: 10.1177/0961203310395803.


The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or pregnancy morbidity in combination with the persistent presence of circulating antiphospholipid antibodies: lupus anticoagulant, anticardiolipin antibodies and/or anti-β2-glycoprotein I antibodies in medium to high titers. The management of thrombosis in patients with APS is a subject of controversy. This set of recommendations is the result of an effort to produce guidelines for therapy within a group of specialist physicians in Cardiology, Neurology, Hematology, Rheumatology and Internal Medicine, with a clinical and research focus on APS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Advisory Committees
  • Antibodies, Antiphospholipid / adverse effects
  • Antibodies, Antiphospholipid / blood*
  • Antiphospholipid Syndrome / blood*
  • Antiphospholipid Syndrome / complications
  • Antiphospholipid Syndrome / immunology*
  • Clinical Trials as Topic
  • Congresses as Topic
  • Female
  • Humans
  • Pregnancy
  • Texas
  • Thrombosis / blood
  • Thrombosis / etiology
  • Thrombosis / prevention & control*
  • Thrombosis / therapy*


  • Antibodies, Antiphospholipid