[Rheumatology. TNF alpha-inhibitors: infection risks? Practical recommendations]

Rev Med Suisse. 2011 Jan 12;7(277):75-6, 78-9.
[Article in French]


Anti-TNF alpha are immunomodulatory treatments prescribed for some rheumatologic inflammatory diseases (ex: spondylarthropathy, rheumatoid polyarthritis). The randomised studies suggested that anti-TNF alpha therapy is associated with an overall risk of infectious diseases. The results of the observational studies are more reassuring. In this article, we will describe some results of theses studies and propose some practical recommendations in use of the anti-TNF alpha therapy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antirheumatic Agents / adverse effects*
  • Bacterial Infections / etiology
  • Bacterial Infections / prevention & control
  • Humans
  • Opportunistic Infections / etiology
  • Opportunistic Infections / prevention & control
  • Rheumatic Diseases / drug therapy*
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*


  • Antirheumatic Agents
  • Tumor Necrosis Factor-alpha