Plant systems biology: network matters

Plant Cell Environ. 2011 Apr;34(4):535-53. doi: 10.1111/j.1365-3040.2010.02273.x. Epub 2011 Feb 11.

Abstract

Systems biology is all about networks. A recent trend has been to associate systems biology exclusively with the study of gene regulatory or protein-interaction networks. However, systems biology approaches can be applied at many other scales, from the subatomic to the ecosystem scales. In this review, we describe studies at the sub-cellular, tissue, whole plant and crop scales and highlight how these studies can be related to systems biology. We discuss the properties of system approaches at each scale as well as their current limits, and pinpoint in each case advances unique to the considered scale but representing potential for the other scales. We conclude by examining plant models bridging different scales and considering the future prospects of plant systems biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Gene Regulatory Networks*
  • Metabolic Networks and Pathways*
  • Models, Biological
  • Molecular Biology
  • Plant Roots / metabolism
  • Plants / genetics
  • Plants / metabolism*
  • Plants / ultrastructure
  • Protein Interaction Domains and Motifs
  • Systems Biology* / methods
  • Systems Biology* / trends