Sex dependence of airflow limitation and air trapping in children with severe asthma

J Allergy Clin Immunol. 2011 Apr;127(4):1073-4. doi: 10.1016/j.jaci.2010.12.1079.


In this cross-sectional evaluation of 77 severe and 71 non-severe asthmatics ages 6–17, boys, unlike girls with severe asthma, exhibited adult-like patterns of air-trapping and post-bronchodilator airflow limitation, apparently coincident with the onset of the severe asthma phenotype.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Asthma / physiopathology*
  • Child
  • Female
  • Humans
  • Male
  • Respiratory Function Tests
  • Sex Factors