Pregnancy in women with Type 1 and Type 2 diabetes in Dublin

Ir J Med Sci. 2011 Jun;180(2):469-73. doi: 10.1007/s11845-011-0682-8. Epub 2011 Feb 11.

Abstract

Introduction: The Confidential Enquiry into Maternal and Child Health (CEMACH) reported outcomes of pregnancies in women with pre-gestational diabetes (PGDM) in the UK (n = 3,733). This study aimed to compare CEMACH outcomes with PGDM pregnancies in Dublin.

Methods: Retrospective chart review of all PGDM pregnancies. Comparison to CEMACH are shown in brackets.

Results: One hundred and ten PGDM women delivered in Dublin. Thirty (27%) had T2 diabetes (vs. 27%). Fifty-nine (53%) women had a booking HbA1c less than 7% (vs. 66%). Nineteen women (17.3%) had a first trimester miscarriage (vs. 8.5%). Of the 91 remaining women, 71 (78%) women underwent induction of labour (vs. 38.9%). Fifty-four women (59.3%) were delivered by caesarean section (vs. 67.4%). Two infants (2.1%) were macrosomic (vs. 5.7%). There was one intrauterine death (0.1 vs. 0.6%) and no maternal deaths (vs. five).

Conclusion: These results serve to underline the continued importance of multidisciplinary care for pregnant women with diabetes.

MeSH terms

  • Abortion, Spontaneous / epidemiology
  • Cesarean Section
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Fetal Macrosomia / epidemiology
  • Fetal Mortality
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Ireland / epidemiology
  • Labor, Induced
  • Pregnancy
  • Pregnancy Outcome*
  • Pregnancy in Diabetics*
  • Premature Birth
  • Prenatal Care
  • Retrospective Studies

Substances

  • Glycated Hemoglobin A