Surgical site infections

Infect Dis Clin North Am. 2011 Mar;25(1):135-53. doi: 10.1016/j.idc.2010.11.004.


Surgical site infections (SSIs) lead to adverse patient outcomes, including prolonged hospitalization and death. Wound contamination occurs with each incision, but proven strategies exist to decrease the risk of SSIs. In particular, improved adherence to evidence-based preventative measures related to appropriate antimicrobial prophylaxis can decrease the rate of SSI. Aggressive surgical debridement and effective antimicrobial therapy are needed to optimize the treatment of SSIs.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Antibiotic Prophylaxis
  • Blood Glucose / metabolism
  • Cross Infection / prevention & control*
  • Cross Infection / therapy*
  • Debridement
  • Equipment Contamination / prevention & control
  • Evidence-Based Medicine
  • Humans
  • Risk Factors
  • Surgical Wound Infection / prevention & control*
  • Surgical Wound Infection / therapy*


  • Anti-Bacterial Agents
  • Blood Glucose