Meckel's diverticulum: a review

Clin Anat. 2011 May;24(4):416-22. doi: 10.1002/ca.21094. Epub 2011 Feb 14.


Meckel's diverticulum is the most prevalent congenital abnormality of the gastrointestinal tract. This anomaly is due to the incomplete obliteration of the omphalomesenteric duct during the 7th week of gestation and is classically located 2 feet proximal to the ileocecal valve. Variations of this congenital malformation have been recorded based on location, size, and form. While most of the population may be asymptomatic, clinical manifestation, including gastrointestinal bleed and intestinal obstruction, can emerge. Despite the frequency of Meckel's diverticulum, it is commonly misdiagnosed due to its mimicry of appendicitis. This article aimed to review this derailment of embryological development.

Publication types

  • Review

MeSH terms

  • Appendicitis / diagnosis
  • Asymptomatic Diseases
  • Diagnosis, Differential
  • Diverticulitis / diagnosis*
  • Diverticulitis / therapy
  • Gestational Age
  • Humans
  • Ileocecal Valve / pathology
  • Meckel Diverticulum / embryology
  • Meckel Diverticulum / pathology*