Antibacterial activities of imidazolium, pyrrolidinium and piperidinium salts

Noritaka Iwai; Kyosuke Nakayama; Tomoya Kitazume

doi:10.1016/j.bmcl.2011.01.081

Antibacterial activities of imidazolium, pyrrolidinium and piperidinium salts

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1728-30. doi: 10.1016/j.bmcl.2011.01.081. Epub 2011 Jan 31.

Authors

Noritaka Iwai¹, Kyosuke Nakayama, Tomoya Kitazume

Affiliation

¹ Graduate School of Bioscience and Bioengineering, Tokyo Institute of Technology, Midori-ku, Yokohama, Japan.

PMID: 21324694
DOI: 10.1016/j.bmcl.2011.01.081

Abstract

The antibacterial activity of various types of imidazolium, pyrrolidinium and piperidinium salts with both propargyl group and alkyl and/or silylalkyl chains of different lengths, are described. Especially, the MIC (μg/ml) of prepared each compound for Escherichia coli and other several bacteria was determined.

MeSH terms

Anti-Bacterial Agents / pharmacology*
Imidazoles / pharmacology*
Microbial Sensitivity Tests
Piperidines / pharmacology*
Pyrroles / pharmacology*

Substances

Anti-Bacterial Agents
Imidazoles
Piperidines
Pyrroles