The contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda

AIDS. 2011 Mar 27;25(6):863-5. doi: 10.1097/QAD.0b013e3283448790.


We determined HIV infections in the Rakai cohort before (82/9434) and after (131/13082) the availability of antiretroviral therapy (ART). The proportions of total HIV infections pre-ART and post-ART were 18.3% and 13.7%, respectively, among identifiable HIV-discordant couples, 23.2% and 26.0%, respectively, in concordant HIV-negative couples, 29.3% and 17.6% in married persons with unknown partner status, and 29.3% and 42.7% in the unmarried. Voluntary counseling and testing targeting discordant couples is unlikely to have a substantial impact in this setting.

MeSH terms

  • Counseling
  • Female
  • HIV Infections / psychology*
  • HIV Infections / transmission
  • Humans
  • Male
  • Sexual Behavior / psychology*
  • Sexual Partners*
  • Uganda