The purpose of the present study was determination of the percentage of polymorphonuclear granulocytes (PMNL) with Fc (FcRs) and "non-immunological" (INsRs) receptors on the surface in clinically healthy cows. In the study the PMNL populations were compared after their isolation from the peripheral blood, the mammary gland and the uterus. For the determination of FcRs and INsRs the rosette test and the phagocytosis test were chosen. The reported study demonstrated that a significantly higher PMNL proportion isolated from the colostrum, milk or uterine lumen (48 h after ovulation) had on the surface greater number of FcRs than the PMNL isolated from the peripheral blood of the same cows. These cells had also a higher phagocytic activity against two standard strains of S. aureus (Smith and 305).