Genetic approaches to myofibril form and function in Drosophila

Trends Genet. 1990 Apr;6(4):126-31. doi: 10.1016/0168-9525(90)90127-r.


Myofibrils, the contractile organelles of muscle, are apt subjects for studies on the formation and function of actomyosin networks. Molecular genetic approaches are advancing our understanding of myofibril structure and assembly, and may offer a novel and useful approach for investigating the crossbridge cycle. We review recent progress in Drosophila.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Drosophila melanogaster / genetics*
  • Exons
  • Muscle Contraction
  • Muscle Proteins / genetics
  • Mutation
  • Myofibrils / physiology*
  • Myosins / genetics


  • Muscle Proteins
  • Myosins