[Polypharmacy is an indicator for a poor prognosis, which is not altered by deprescribing in nursing home]

Praxis (Bern 1994). 2011 Feb 16;100(4):213-20. doi: 10.1024/1661-8157/a000431.
[Article in German]

Abstract

Aim: To examine the influence of polypharmacy ordered by the pretreating site and deprescribing (i.e. the appropriate withdrawal of prescribed drugs) by the nursing home physician on survival time.

Methods: Retrospective Analysis of medical databasis from 1,249 patients, thereof 611 in a nursing home with practice of deprescribing.

Results: 70% of the patients with excessive polypharmacy (>9 drugs), 57% of those with polypharmacy (6 to 9 drugs) and 43% of the remaining patients (<6 drugs) deceased within 286 days after admission (chi-squared 2 DF = 43.72; p <0.001). Deprescribing by the nursing home physician at admission revealed no influence on survival time.

Conclusion: Polypharmacy is not the reason, but an indicator for a poor prognosis, which is not altered by deprescribing.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Aged, 80 and over
  • Drug Prescriptions*
  • Drug Utilization*
  • Female
  • Homes for the Aged*
  • Humans
  • Male
  • Nursing Homes*
  • Polypharmacy*
  • Prognosis
  • Retrospective Studies
  • Survival*