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Randomized Controlled Trial
. 2011 Jun;101(6):1096-102.
doi: 10.2105/AJPH.2010.196048. Epub 2011 Feb 17.

The effect of peer-driven intervention on rates of screening for AIDS clinical trials among African Americans and Hispanics

Marya Viorst Gwadz  1 , Noelle R Leonard, Charles M Cleland, Marion Riedel, Angela Banfield, Donna Mildvan; ACT2 Project Collaborative Research Team
Affiliations
Randomized Controlled Trial

The effect of peer-driven intervention on rates of screening for AIDS clinical trials among African Americans and Hispanics

Marya Viorst Gwadz et al. Am J Public Health. 2011 Jun.

Erratum in

  • Am J Public Health. 2011 Oct;101(10):1815

Abstract

Objectives: We examined the efficacy of a peer-driven intervention to increase rates of screening for AIDS clinical trials among African Americans and Hispanics living with HIV/AIDS.

Methods: We used a randomized controlled trial design to examine the efficacy of peer-driven intervention (6 hours of structured sessions and the opportunity to educate 3 peers) compared with a time-matched control intervention. Participants were recruited using respondent-driven sampling (n = 342; 43.9% female; 64.9% African American, 26.6% Hispanic). Most participants (93.3%) completed intervention sessions and 64.9% recruited or educated peers. Baseline and post-baseline interviews (94.4% completed) were computer-assisted. A mixed model was used to examine intervention effects on screening.

Results: Screening was much more likely in the peer-driven intervention than in the control arm (adjusted odds ratio [AOR] = 55.0; z = 5.49, P < .001); about half of the participants in the intervention arm (46.0%) were screened compared with 1.6% of controls. The experience of recruiting and educating each peer also increased screening odds among those who were themselves recruited and educated by peers (AOR = 1.4; z = 2.06, P < .05).

Conclusions: Peer-driven intervention was highly efficacious in increasing AIDS clinical trial screening rates among African Americans and Hispanics living with HIV/AIDS.

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Figures

FIGURE 1
FIGURE 1
Overview of the ACT2 Project, New York, NY, 2008–2009. Note. ACT = AIDS clinical trial.
See this image and copyright information in PMC

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