Improving human forensics through advances in genetics, genomics and molecular biology

Nat Rev Genet. 2011 Mar;12(3):179-92. doi: 10.1038/nrg2952.


Forensic DNA profiling currently allows the identification of persons already known to investigating authorities. Recent advances have produced new types of genetic markers with the potential to overcome some important limitations of current DNA profiling methods. Moreover, other developments are enabling completely new kinds of forensically relevant information to be extracted from biological samples. These include new molecular approaches for finding individuals previously unknown to investigators, and new molecular methods to support links between forensic sample donors and criminal acts. Such advances in genetics, genomics and molecular biology are likely to improve human forensic case work in the near future.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • DNA Fingerprinting / methods*
  • Databases, Genetic
  • Female
  • Forensic Medicine / methods*
  • Forensic Medicine / trends*
  • Genetic Markers
  • Genomics*
  • Humans
  • Male


  • Genetic Markers