A patient with Crohn's disease who presented with thrombotic thrombocytopenic purpura/hemolytic uremic syndrome

Ren Fail. 2011;33(2):244-5. doi: 10.3109/0886022X.2010.541577.


Thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) is characterized with fever, purpura, anemia due to microangiopathic hemolysis, thrombocytopenia, kidney damage, and neurologic symptoms. The development of TTP/HUS during the course of inflammatory bowel diseases was rarely reported. However, coexistence of TTP/HUS and Crohn's disease in the same patient has not been reported previously. We herein present a case of TTP/HUS who presented with Crohn's disease. He responded to cyclosporine treatment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Crohn Disease / complications*
  • Female
  • Hemolytic-Uremic Syndrome / complications*
  • Humans
  • Purpura, Thrombotic Thrombocytopenic / complications

Supplementary concepts

  • Thrombotic thrombocytopenic purpura, acquired