Treatment of bromhidrosis with a glycine-soja sterocomplex topical product

J Cosmet Dermatol. 2011 Mar;10(1):74-7. doi: 10.1111/j.1473-2165.2010.00536.x.


Aims: Bromhidrosis is a common problem with a severe negative impact on the patient's social and emotional life. The objective of this open-label study was to evaluate the efficacy and safety of a local product with the main active ingredient of glycine-soja sterocomplex in the treatment of local bromhidrosis.

Patients/methods: Eighteen patients with axillary bromhidrosis and eight patients with bromhidrosis of the genital area were included. Bromhidrosis was evaluated through a sniff test of a worn garment on a four-point scale. Patients applied a glycine-soja sterocomplex topical agent twice daily on the affected areas for 15 days and bromhidrosis was evaluated again.

Results: Subjective mean level of bromhidrosis at baseline was 3.50 ± 0.50 and after treatment 1.53 ± 0.51. Mean impact on quality of life at baseline was 3.30 ± 0.48 and after treatment 1.30 ± 0.49. Investigators objective evaluation revealed an improvement in intensity of odor from 3.23 ± 0.83 to 1.53 ± 0.53 and in acceptability of odor from 3.1 ± 1.01 to 1.65 ± 0.76.

Conclusions: The glycine-soja sterocomplex topical agent shows encouraging improvement on both the intensity and quality of odor in patients with bromhidrosis and has a profound improvement on the patients' quality of life without any side effects.

MeSH terms

  • Administration, Topical
  • Adult
  • Aged
  • Axilla / physiopathology
  • Female
  • Genitalia / physiopathology
  • Glycine max
  • Humans
  • Hyperhidrosis / drug therapy*
  • Male
  • Middle Aged
  • Odorants / prevention & control*
  • Phytotherapy*
  • Plant Extracts / therapeutic use*
  • Quality of Life*
  • Sweat / microbiology
  • Young Adult


  • Plant Extracts