Therapies aimed at the gut microbiota and inflammation: antibiotics, prebiotics, probiotics, synbiotics, anti-inflammatory therapies

Gastroenterol Clin North Am. 2011 Mar;40(1):207-22. doi: 10.1016/j.gtc.2010.12.009.


Several recent observations have raised the possibility that disturbances in the gut microbiota and/or a low-grade inflammatory state may contribute to symptomatology and the etiology of irritable bowel syndrome (IBS). Consequent on these hypotheses, several therapeutic categories have found their way into the armamentarium of those who care for IBS sufferers. These agents include probiotics, prebiotics, antibiotics, and anti-inflammatory agents.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Anti-Inflammatory Agents / therapeutic use*
  • Humans
  • Irritable Bowel Syndrome / microbiology*
  • Irritable Bowel Syndrome / physiopathology
  • Irritable Bowel Syndrome / therapy*
  • Prebiotics*
  • Probiotics / therapeutic use*
  • Synbiotics*


  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Prebiotics