Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data

Magnes Res. 1990 Jun;3(2):109-12.


This paper describes how the authors, after examining the calcium modulating action of the Mg ion and its antihistamine-like action, tested a salt containing Mg (Mg pidolate, MAG2) in the clinical treatment of seasonal allergic rhinitis. A total of 38 hayfever subjects were studied. They were given 1.5 g Mg salt three times a day for one month (oral MAG2 vials); placebo was used as a control in a randomized double-blind study. The efficacy of the product was assessed using the following criteria: intensity of rhinorrhoea, daily consumption of Kleenex tissues, number of sneezes in a day, intensity of lacrimation. The results were analysed using Student's t test and demonstrated the clinical efficacy of the product in the control of seasonal allergic rhinitis symptoms (P less than 0.001).

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Calcium / metabolism*
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Lacrimal Apparatus / drug effects
  • Magnesium / pharmacology*
  • Male
  • Mucus / drug effects
  • Rhinitis, Allergic, Seasonal / drug therapy*
  • Sneezing / drug effects


  • Magnesium
  • Calcium