Schiglautone A, a new tricyclic triterpenoid with a unique 6/7/9-fused skeleton from the stems of Schisandra glaucescens

Org Lett. 2011 Mar 18;13(6):1502-5. doi: 10.1021/ol200188n. Epub 2011 Feb 21.

Abstract

Schiglautone A (1), a unique 6/7/9-fused tricyclic carbon backbone triterpenoid, was isolated from the stems of Schisandra glaucescens. Its structure was determined on the basis of spectroscopic analysis and single-crystal X-ray crystallography. A hypothetical biosynthetic pathway of 1 was postulated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Cyclooctanes
  • Lignans
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Stems / chemistry
  • Polycyclic Compounds
  • Schisandra / chemistry*
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification*

Substances

  • Cyclooctanes
  • Lignans
  • Polycyclic Compounds
  • Triterpenes
  • schiglautone A
  • schizandrin