Predictors of outcome in patients with prosthetic valve endocarditis (PVE) and potential advantages of homograft aortic root replacement for prosthetic ascending aortic valve-graft infections

J Card Surg. 1990 Mar;5(1):53-62. doi: 10.1111/j.1540-8191.1990.tb00737.x.


Seventy-five surgically treated patients with prosthetic valve endocarditis were treated at the Stanford University Medical Center. This was a multivariate analysis analyzing both patient related factors, bacteriology, and surgical findings. The conclusions among 10 patients with allograft valves, 20% had an annular abscess; this occurred in 36% of 29 patients with porcine valves, and 65% of these with mechanical prosthesis. Though prevention, again, is key in this especially devastating disease, once infection has been established and an aggressive approach is indicated, it would appear that a homograft re-replacement or free aortic homograft valve replacement can deal with severe tissue destruction to prevent recurrence.

MeSH terms

  • Abscess / surgery
  • Adult
  • Aorta / transplantation*
  • Aortic Valve / transplantation*
  • Candidiasis / surgery
  • Child
  • Endocarditis / microbiology
  • Endocarditis / surgery
  • Endocarditis, Bacterial / surgery*
  • Female
  • Heart Valve Prosthesis / adverse effects*
  • Humans
  • Probability
  • Prosthesis-Related Infections / surgery*
  • Staphylococcal Infections / surgery
  • Staphylococcus epidermidis
  • Survival Rate
  • Transplantation, Homologous
  • Treatment Outcome