A simple and reliable analytical method for analysis of fluroxypyr-meptyl residue in rice, soil and water was investigated. The residue levels and dissipation rates of fluroxypyr-meptyl (34% AS) were determined by GC-MSD in selected ion monitoring mode. In the supervised field trials, the half-life of fluroxypyr- meptyl in rice plant was in the range 1.25-4.13 days. The half-lives of fluroxypyr-meptyl in soil and water were 2.29 and 1.73 days, respectively. In order to assess the dissipation of fluroxypyr-meptyl in the environment, a laboratory simulated experiment was carried out in soil and water. The terminal residues of fluroxypyr-meptyl in rice plant, husked rice, rice hull and soil samples were undetectable at harvest. It showed that fluroxypyr-meptyl may be safe to use according to the recommended dosage suggested by the corporation.