S(N)Ar reactions of nitro-(pentafluorosulfanyl)benzenes to generate SF5 aryl ethers and sulfides

Petr Beier; Tereza Pastýříková; Norbert Vida; George Iakobson

doi:10.1021/ol2001478

S(N)Ar reactions of nitro-(pentafluorosulfanyl)benzenes to generate SF5 aryl ethers and sulfides

Org Lett. 2011 Mar 18;13(6):1466-9. doi: 10.1021/ol2001478. Epub 2011 Feb 22.

Authors

Petr Beier¹, Tereza Pastýříková, Norbert Vida, George Iakobson

Affiliation

¹ Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. beier@uochb.cas.cz

PMID: 21341714
DOI: 10.1021/ol2001478

Abstract

Nucleophilic aromatic substitution of the nitro group of para- and meta-nitro-(pentafluorosulfanyl)benzene with alkoxides and thiolates generates a range of substituted 4- and 3-(pentafluorosulfanyl)benzenes in a single-step reaction.