Home versus clinic-based specimen collection for Chlamydia trachomatis and Neisseria gonorrhoeae

Expert Rev Anti Infect Ther. 2011 Feb;9(2):183-94. doi: 10.1586/eri.10.164.


Sexually transmitted infections (STIs) are a major public health concern that must be addressed with innovative screening methods to supplement traditional approaches. Home-based screening with self-collected urine or vaginal specimens is a highly feasible and acceptable method, and shows promise in improving STI screening rates in both men and women. Home collection kits have been offered in a variety of settings, with results ranging from very modest improvements in screening rates to 100-fold increases beyond the rates observed with clinic-based screening. This article describes and evaluates the effectiveness and limitations of various home screening strategies used for the detection of STIs.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Chlamydia Infections / diagnosis*
  • Chlamydia Infections / microbiology
  • Chlamydia trachomatis / isolation & purification
  • Female
  • Gonorrhea / diagnosis*
  • Gonorrhea / microbiology
  • Humans
  • Male
  • Neisseria gonorrhoeae / isolation & purification
  • Randomized Controlled Trials as Topic
  • Reagent Kits, Diagnostic*
  • Self Care*
  • Sexually Transmitted Diseases, Bacterial / diagnosis
  • Sexually Transmitted Diseases, Bacterial / microbiology
  • Specimen Handling / methods*
  • Urine / microbiology
  • Vagina / microbiology


  • Reagent Kits, Diagnostic