Susceptibility to antibiotics of Vibrio spp. and Photobacterium damsela ssp. piscicida strains isolated from Italian aquaculture farms

New Microbiol. 2011 Jan;34(1):53-63. Epub 2011 Jan 15.


The antibiotic resistance patterns of aetiological agents responsible for vibriosis and pasteurellosis were studied to contribute to control the spread of these two bacterial diseases in Mediterranean fish farming. Strains of Photobacterium damsela ssp. piscicida, Vibrio fluvialis, Vibrio alginolyticus, Vibrio parahaemolyticus, Vibrio metschnikovii, isolated from Italian aquaculture (fish, shellfish and crustaceans) sites, were assayed for their susceptibility to some antibacterial agents currently used in farming practices. Kirby Bauer and Minimum Inhibitory Concentration (M.I.C.) tests were performed. The bacterial strains showed resistance to ampicillin, carbenicillin, kanamycin, cefalothin, while they were sensitive to chloramphenicol, nitrofurantoin and tobramycin; the sulfadiazine-trimethoprim association was completely ineffective. Conversely, flumequine showed the lowest M.I.C. value (0.97 �g mL-1), suggesting its marked antibiotic effect. Considering that quinolone resistance can be transmitted only by selection of mutations and not by other genetic mechanisms, this study stresses the importance of a more responsible use of this antibacterial drug in aquaculture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Aquaculture
  • Bacterial Typing Techniques / veterinary
  • Bass / microbiology*
  • Crustacea / microbiology*
  • Drug Resistance, Bacterial
  • Fish Diseases / microbiology
  • Italy
  • Microbial Sensitivity Tests / veterinary
  • Mollusca / microbiology*
  • Pasteurella Infections / microbiology
  • Pasteurella Infections / veterinary
  • Photobacterium / classification
  • Photobacterium / drug effects*
  • Photobacterium / isolation & purification
  • Vibrio / classification
  • Vibrio / drug effects*
  • Vibrio / isolation & purification
  • Vibrio Infections / microbiology
  • Vibrio Infections / veterinary


  • Anti-Bacterial Agents