Standing guard at the mucosa

M Juliana McElrath

doi:10.1016/j.immuni.2011.02.014

Standing guard at the mucosa

Immunity. 2011 Feb 25;34(2):146-8. doi: 10.1016/j.immuni.2011.02.014.

Author

M Juliana McElrath¹

Affiliation

¹ Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle, WA 98109, USA.

PMID: 21349427
DOI: 10.1016/j.immuni.2011.02.014

Abstract

Most successful vaccines elicit antibodies that protect against infection. In this issue of Immunity, Bomsel et al. (2011) show in the rhesus macaque model that vaccine-induced mucosal antibodies, rather than circulating neutralizing antibodies, may be critical components for protective immunity against HIV-1.

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