Shining a light on energy homeostasis

Masoud Ghamari-Langroudi; Roger D Cone

doi:10.1016/j.cmet.2011.02.007

Shining a light on energy homeostasis

Cell Metab. 2011 Mar 2;13(3):235-6. doi: 10.1016/j.cmet.2011.02.007.

Authors

Masoud Ghamari-Langroudi¹, Roger D Cone

Affiliation

¹ Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-0615, USA.

Abstract

The hypothalamic arcuate nucleus is a complex structure containing both orexigenic and anorexigenic neurons, coordinately regulated by leptin and energy state. In their recent Nature Neuroscience study, Aponte et al. (2011) use optogenetic technology to provide a glimpse into the consequences of exclusive activation of either NPY/AgRP or POMC neurons.

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