[Isolation and identification of chemical constituents from Taxus cuspidta Sibe et Zucc]

Yao Xue Xue Bao. 2010 Nov;45(11):1398-401.
[Article in Chinese]

Abstract

Three compounds were isolated from the extract of Taxus cuspidta Sibe et Zucc with the column chromatography on silica gel and preparative HPLC methods. Their structures were identified according to the physicochemical properties and spectral analysis, and they were identified as (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol (1), 2-deacetoxy-7beta, 9a, 10beta-trideacetyltaxinine J (2) and (3aS, 4aR, 6S, 8S, 8aS, 9R, 10R, 10aS)-benz[f]azulene-6, 8, 9, 10 (3H)-terol, 3a, 4, 4a, 5, 6, 7, 8, 8a, 9, 10-decahydro-10a-(1-hydroxyl-1-methylethyl)-1, 8a-dimethyl-5-methylene (3). Among them, compound 1 was a new compound, and compounds 2, 3 were two novel natural products.

Publication types

  • English Abstract

MeSH terms

  • Azulenes / chemistry
  • Azulenes / isolation & purification
  • Coumarins / chemistry
  • Coumarins / isolation & purification*
  • Inositol / analogs & derivatives*
  • Inositol / chemistry
  • Inositol / isolation & purification
  • Molecular Structure
  • Plants, Medicinal / chemistry*
  • Taxoids / chemistry
  • Taxoids / isolation & purification*
  • Taxus / chemistry*

Substances

  • (3aS,4aR,6S,8S,8aS,9R,10R,10aS)-benz(f)azulene-6,8,9,10(3H)-terol,3a,4,4a,5, 6,7,8,8a,9,10-decahydro-10a-(1-hydroxyl-1-methylethyl)-1,8a-dimethyl-5-methylene
  • (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol
  • 2-deacetoxy-7beta,9a,10beta-trideacetyltaxinine J
  • Azulenes
  • Coumarins
  • Taxoids
  • Inositol