Epidemiologic, clinical, and genetic studies provide grounds for differentiation of juvenile spondyloarthropathies from other rheumatic diseases. The prevalence of spondyloarthropathies among whites is estimated at 0.7 to 1.2% and the female-to-male ratio is 1:2.5. The current classification of clinically defined and undefined forms of juvenile spondyloarthropathies is presented together with their diagnostic criteria and treatment.