Surface contact toxicity and synergism of several insecticides against different stages of the tropical bed bug, Cimex hemipterus (Hemiptera: Cimicidae)

Pest Manag Sci. 2011 Jun;67(6):734-40. doi: 10.1002/ps.2123. Epub 2011 Mar 2.

Abstract

Background: Five formulated insecticides (lambda-cyhalothrin at 10 mg m⁻², bifenthrin at 50 mg m⁻², fipronil at 10 mg m⁻², fenitrothion at 50 mg m⁻², imidacloprid at 5 mg m⁻²) and one active ingredient (DDT at 500 mg m⁻²) were evaluated using a surface contact method against early and late instars and adults of two strains of the tropical bed bug, Cimex hemipterus (F.). Synergism of lambda-cyhalothrin and fipronil using piperonyl butoxide (PBO) was also assessed.

Results: The order of susceptibility of different stages of bed bugs was as follows: early stage-lambda-cyhalothrin > bifenthrin = imidacloprid > fipronil > fenitrothion > DDT; late stage-lambda-cyhalothrin > bifenthrin > fenitrothion > imidacloprid > fipronil > DDT; adult-lambda-cyhalothrin > imidacloprid > bifenthrin > fenitrothion > fipronil > DDT. The late instars exhibited significantly higher LT₅₀ among the life stages. The addition of PBO to fipronil increased the susceptibility of the insects.

Conclusions: Lambda-cyhalothrin, bifenthrin, fenitrothion and fipronil at the recommended application rates were effective against C. hemipterus. Although imidacloprid demonstrated good initial response against C. hemipterus, the insects showed substantial recovery 72 h post-treatment. The late instars (fourth and fifth instars) should be used as the model for toxicological evaluation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bedbugs / drug effects*
  • Bedbugs / growth & development*
  • Bedbugs / physiology
  • DDT / pharmacology
  • Drug Synergism
  • Female
  • Fenitrothion / pharmacology
  • Imidazoles / pharmacology
  • Insecticides / pharmacology*
  • Life Cycle Stages / drug effects*
  • Male
  • Neonicotinoids
  • Nitriles / pharmacology
  • Nitro Compounds / pharmacology
  • Pesticide Synergists / pharmacology*
  • Piperonyl Butoxide / pharmacology
  • Pyrazoles / pharmacology
  • Pyrethrins / pharmacology
  • Time Factors
  • Tropical Climate

Substances

  • Imidazoles
  • Insecticides
  • Neonicotinoids
  • Nitriles
  • Nitro Compounds
  • Pesticide Synergists
  • Pyrazoles
  • Pyrethrins
  • imidacloprid
  • bifenthrin
  • DDT
  • Piperonyl Butoxide
  • fipronil
  • cyhalothrin
  • Fenitrothion