Gardenoins E-H, cycloartane triterpenes from the apical buds of Gardenia obtusifolia

Thanesuan Nuanyai; Ruengrit Sappapan; Tirayut Vilaivan; Khanitha Pudhom

doi:10.1248/cpb.59.385

Gardenoins E-H, cycloartane triterpenes from the apical buds of Gardenia obtusifolia

Chem Pharm Bull (Tokyo). 2011;59(3):385-7. doi: 10.1248/cpb.59.385.

Authors

Thanesuan Nuanyai¹, Ruengrit Sappapan, Tirayut Vilaivan, Khanitha Pudhom

Affiliation

¹ Research Centre of Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

PMID: 21372423
DOI: 10.1248/cpb.59.385

Abstract

Four new cycloartane triterpenes, named gardenoins E-H (1-4), were isolated from the apical buds of Gardenia obtusifolia, together with five known cycloartanes. Only compound 1 displayed cytotoxicity against colon, hepatic and lung cancer cell lines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Gardenia / chemistry*
Humans
Magnetic Resonance Spectroscopy
Molecular Conformation
Triterpenes / chemistry*
Triterpenes / isolation & purification
Triterpenes / toxicity

Substances

Triterpenes
cycloartane