Arsenic and Its Speciation in Water Samples by High Performance Liquid Chromatography Inductively Coupled Plasma Mass Spectrometry--Last Decade Review

Talanta. 2011 Apr 15;84(2):247-61. doi: 10.1016/j.talanta.2010.10.065. Epub 2011 Jan 26.


Arsenic composes a danger for human health all over the world as it is responsible for water resources contamination. The toxicity of arsenic depends on its chemical form. However, occurrence of particular arsenic species is dependent on processes occurring in water. Nowadays, more arsenic species is detected and analyzed in different kind of water (mineral, tap, waste), mainly owing to great possibilities resulting from coupling high performance liquid chromatography (HPLC) with inductively coupled plasma mass spectrometry (ICP-MS). This review mainly describes arsenic speciation analysis by HPLC-ICP-MS technique on the basis of articles that have been published since 2000. Arsenic chemistry, occurrence in different kind of water, total arsenic determination with interferences elimination and its validation and analytical performance are also reviewed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arsenic / analysis*
  • Chromatography, High Pressure Liquid / methods*
  • Mass Spectrometry / methods*
  • Water Pollutants, Chemical / analysis*


  • Water Pollutants, Chemical
  • Arsenic