[Glucocorticoids and gluco-lipidic metabolism]

Sem Hop. 1978 Sep;54(21-24):764-70.
[Article in French]

Abstract

Glucocorticoids increase the stocks of carbohydrate and the supra-hepatic flow of glucose. Their excess produces a centripetal redistribtution of adipose stocks and potentialises adipocyte lipolysis. Although their role of glucose and lipid metabolism is evident, the mechanisms and sites of action of glucocorticoids are multiple and not entirely clear. The actions of glucocorticoids become clear in cases of insulin deficiency, especially when the deficiency is marked, which is of great interest in current medical practice.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adipose Tissue / drug effects
  • Animals
  • Carbohydrate Metabolism*
  • Diabetes Mellitus / metabolism
  • Fatty Acids, Nonesterified / blood
  • Glucocorticoids / pharmacology*
  • Glucocorticoids / physiology
  • Gluconeogenesis / drug effects
  • Glucose / metabolism
  • Humans
  • Lipid Metabolism*
  • Lipid Mobilization / drug effects
  • Liver / drug effects
  • Liver Glycogen / metabolism
  • Muscle Proteins / metabolism
  • Pancreas / drug effects
  • Receptor, Insulin / drug effects
  • Stimulation, Chemical

Substances

  • Fatty Acids, Nonesterified
  • Glucocorticoids
  • Liver Glycogen
  • Muscle Proteins
  • Receptor, Insulin
  • Glucose