Testicular microlithiasis: the importance of self-examination

J Paediatr Child Health. 2014 Oct;50(10):E102-5. doi: 10.1111/j.1440-1754.2011.02021.x. Epub 2011 Mar 10.


Aim: To explore the issue of appropriate management of testicular microlithiasis. We report the third ever case of tumour arising from a testis previously known to have microlithiasis in childhood and review the literature to provide an evidence-based approach to management of testicular microlithiasis.

Methods: Case report and review of previous literature.

Results and conclusions: Although there is a strong association between testicular microlithiasis and testicular malignancy at diagnosis, there are only three reported cases of subsequent tumour development in childhood. Testicular microlithiasis is an increasingly recognised entity. There is insufficient evidence in the current literature to support any regime of clinical surveillance. Self-examination is the most important factor in the early detection of testicular malignancy.

Keywords: germ cell tumour of testis; paediatric; surveillance; testicular microlithiasis; testicular self-examination.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biopsy, Needle
  • Calculi / diagnostic imaging
  • Calculi / pathology*
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Male
  • Neoplasms, Germ Cell and Embryonal / diagnosis
  • Neoplasms, Germ Cell and Embryonal / pathology*
  • Precancerous Conditions / pathology*
  • Risk Assessment
  • Self-Examination / methods*
  • Severity of Illness Index
  • Testicular Diseases / diagnostic imaging
  • Testicular Diseases / pathology*
  • Testicular Neoplasms / diagnosis
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / surgery
  • Treatment Outcome
  • Ultrasonography, Doppler

Supplementary concepts

  • Testicular Germ Cell Tumor
  • Testicular Microlithiasis